|
KMID : 0043320050280111228
|
|
Archives of Pharmacal Research
2005 Volume.28 No. 11 p.1228 ~ p.1232
|
|
|
Antibacterial and Antitumor Macrolides from Streptomyces sp. Is9131
|
|
Zhao Pei-Ji
Fan Li-Ming
Li Guo-Hong
Zhu Na
Shen Yue-Mao
|
|
|
Abstract
|
|
|
|
Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.
|
|
|
KEYWORD
|
|
|
Macrolide, Streptomyces sp. Is9131, Antineoplastic activity, Antibacterial activity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|